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In conditions like polycystic ovary syndrome (PCOS), metformin is often used to improve insulin resistance, while GLP-1based therapies have shown stronger effects on weight loss
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Diabetes Obes Metab , 116
We extended this approach here to detect GLP-1R translocation to late endosomes and lysosomes marked by the lysomotropic dye LysoTracker, facilitated by the spectral overlap of one of the Tb emission peaks with the excitation spectrum of LysoTracker DND99